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The recommendations, known as Option B+, included initiation of lifelong highly active antiretroviral therapy regardless of CD4 count for all HIV‐positive pregnant and breastfeeding mothers. For infants, exclusive breastfeeding for 6 months and antiviral therapy were sanctioned.
filexlib. Objectives: The purpose of this research project was (1) to explore the impact of the Option B+ PMTCT program on the work of healthcare professionals, and (2) to understand pregnant HIV-positive women views and experiences with ART for life, as a way to better manage the Option B+ PMTCT program.
Conclusions: The use of Option B+ as PMTCT intervention was found to be more effective in reducing MTCT of HIV compared to other options. Scaling up access to life-long ART and improving retention for women on treatment can potentially reduce further vertical transmission. Introduction
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Results: If implemented as recommended by the World Health Organization, options A, B and B+ are equivalent in preventing new infant infections, yielding cost effectiveness ratios between US$ 37 and US$ 69 per disability adjusted life year averted in children.
In pregnant women: HIV transmission from mother-to-child may be reduced by ART. The protocol called Option B+ is the internationally preferred protocol. All HIV-infected pregnant women receive lifelong triple-drug therapy, regardless of the CD4 count or clinical stage, both for their own health and to prevent transmission to the child. Background: The Ministry of Health in Malawi is implementing a pragmatic and innovative approach for the management of all HIV-infected pregnant women, termed Option B+, which consists of providing life-long antiretroviral treatment, regardless of their CD4 count or clinical stage. Our objective was to determine if Option B+ represents a cost-effective option.
start all HIV-infected pregnant women on lifelong ART, irrespective of whether they are eligible as per clinical guidelines (Option B+). This could also have a significant impact on the prevention of HIV transmission both to children and to sexual partners. Additionally, safer conception is
Keywords: PMTCT, Option B+, Retention, Sensitivity, Specificity Background In 2015, the World Health Organization (WHO) recom-mended that all HIV-positive pregnant women be pro-vided with lifelong antiretroviral therapy (ART) regardless of their CD4 count and WHO staging, also called “option B+” [1]. Compared to previous prevention
ARV Options for PMTCT. Under . Option B+, all HIV-positive women are initiated on triple ART upon diagnosis and continued for life, without interruption, regardless of CD4 status. In countries where Option B+ is not yet adopted, the protocol can be as follows. All HIV-positive pregnant women currently eligible for
As part of its plan to eliminate mother-to-child HIV transmission, Cameroon has adopted since 2014, the WHO HIV Prevention of mother-to-child transmission program, call Option B+ which
The underlying rationale of the Malawi ‘Option B+’ programme was to provide a highly effective antiretroviral therapy (ART) intervention during pregnancy and the prolonged breastfeeding period (typically 24 months in Malawi), in the setting of limited CD4 + cell count testing and high fertility.
The underlying rationale of the Malawi ‘Option B+’ programme was to provide a highly effective antiretroviral therapy (ART) intervention during pregnancy and the prolonged breastfeeding period (typically 24 months in Malawi), in the setting of limited CD4 + cell count testing and high fertility..
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